Hakim, Muhammad Irfan (2025) Development of CelluloseBased Natural Hydrogel Derived from Corncob (Zea Mays L.) Incorporating Liquid Smoke for Wound Dressing Application. Undergraduate thesis, Fakultas Sains dan Matematika Undip.

	Text 1. COVER.pdf Download (245kB)
	Text 5. DAFTAR ISI.pdf Download (90kB)
	Text 10. ABSTRAK.pdf Download (128kB)
	Text 11. BAB I PENDAHULUAN.pdf Download (90kB)
	Archive Muhammad Irfan Hakim.zip Restricted to Repository staff only Download (30MB) | Request a copy

Abstract

Wound infections remain a major healthcare burden, particularly in
developing regions with limited access to sterile environments. Hydrogels offer an
effective solution as wound dressings due to their high fluid absorption and capacity
to deliver bioactive agents. This study presents the development of a sustainable,
cellulose-based hydrogel derived from corncob agricultural waste and
functionalized with liquid smoke containing natural antimicrobial compounds.
Cellulose was extracted via delignification, bleaching, and acid hydrolysis, yielding
67.45% pure cellulose confirmed by FTIR. The hydrogel was synthesized using
epichlorohydrin crosslinking and freeze-drying, resulting in a porous matrix
(average pore diameter 6.3 μm) with excellent swelling capacity (1989%) and
thermal stability up to 273 °C. Liquid smoke with high phenolic content
(123.68 ± 2.72 mg GAE/g) was incorporated at varying concentrations (50%, 75%,
100%). FTIR analysis confirmed successful incorporation, with loading capacity
increasing proportionally to the liquid smoke concentration. The 50% formulation
exhibited the highest exudate absorption (1036.35%), while the 100% formulation
showed the strongest antibacterial activity, with inhibition zones of 3.5 mm and
4.0 mm against Staphylococcus aureus and Escherichia coli, respectively. These
results suggest that corncob-derived cellulose hydrogels infused with liquid smoke
offer a promising approach for advanced wound care applications.

Actions (login required)

View Item