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PENGARUH RUSIP TERHADAPTEKANAN DARAH ARTERI DAN KADAR PROTEIN URINPADA TIKUS PUTIH BUNTING

Wati, Widya and Winarto, Winarto and Johan, Andrew (2013) PENGARUH RUSIP TERHADAPTEKANAN DARAH ARTERI DAN KADAR PROTEIN URINPADA TIKUS PUTIH BUNTING. Masters thesis, Universitas Diponegoro.

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Abstract

Latar Belakang : Konsumsi kandungan garam tinggi pada rusip dapatmenyebabkan peningkatan tekanan darah arteri. Tekanan darah tinggi pada tikushamil menyebabkan proteinuria.Tujuan : penelitian ini menganalisis pengaruh rusip terhadap tekanan darah arteridan kadar protein urin pada tikus hamil.Metode : Desain Penelitian eksperimental pre and post test only control groupdesign menggunakan 21 ekor tikus hamil galur Sprague Dawley usia 3 bulan.Tikus dibagi menjadi 3 kelompok: K0 (kelompok kontrol), K1 rusip(15,4mg/gramBB), K2 rusip (30,8mg/gram BB). Pemeriksaan tekanan daraharteri dan kadar protein urin sebelum perlakuan pada hamil ke-8 hari, setelahperlakuan pada kehamilan ke-20 hari, lamanya perlakuan13 hari.Hasil : Delta tekanan darah arteri kelompok perlakuan lebih tinggi dari kelompokkontrol sebesar 37.43±4.504 (berbeda bermakna p=0.000) namun, delta tekanandarah arteri K2 tidak berbeda (p=0.204) dibanding K1. Delta kadar protein urinkelompok perlakuan lebih tinggi dari kelompok kontrol sebesar 52.97 (45.07-71.18) ( berbeda bermakna p=0.000) dan kadar protein urin K2 lebih tinggi daripada K1.Simpulan : Tekanan darah dan kadar protein urin lebih tinggi pada tikus hamilyang mengkonsumsi rusip.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Tekanan darah arteri, kadar protein urin, rusip
Subjects: Medicine
Divisions: Faculty of Medicine > Master Program in Biomedical Science
Depositing User: heni lutfiatun
Date Deposited: 01 Feb 2023 06:51
Last Modified: 01 Feb 2023 06:51
URI: https://eprints2.undip.ac.id/id/eprint/11584

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