MUSAFILI, Narcisse and Hadisaputro, Suharyo and Sofro, Muchlis AU (2022) INFLUENCE OF EPIDEMIOLOGICAL RISK FACTORS FOR OCCURRENCE OF HEPATITIS B VIRUS (HBV) COINFECTION IN HIV/AIDS PATIENTS: (Study in Dr. Kariadi Hospital, Semarang, Indonesia). Masters thesis, School of Postgraduate Studies.

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	Text 13.CHAPTERII.LITERATURE REVIEW.pdf Download (402kB)
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Abstract

Background: Infection with the hepatitis B virus (HBV) is a major cause of chronic hepatitis, liver cirrhosis, and hepatocellular cancer in people all over the world. Co-infection HIV and HBV is prevalent due to the same routes of transmission.
Objective: To prove several risk factors that influences the occurrence of Hepatitis B virus infection in HIV.AIDS patients in RSUP Dr .Kariadi Hospital Semarang.
Methods: This study used analytical observational design with a case control, a sample of 68(34 cases and 34 controls) For all HIV patients involved in the study, samples were determined by a positive HBsAg test, The dependent variable is occurrence of hepatitis B virus infection in HIV/AIDS patients and the dependent variable is CD4≤100, Age>30,gender,marital status ,level of education ,male who have sex with other male(MSM),Data were analyzed through univariate, bivariate analysis using chi-square and multivariate analysis using logistic regression..
Results: Variables that were proven to influence the occurrence of Hepatitis B virus infection in HIV/AIDS patients after analysis were CD4≤100(p= 0.003 OR=7.535, 95% CI=(2.029-27.990) , being male who do sex with male( MSM) (P=0.027 ,OR=3.544 ,95%CI=(1.158-10.848) The probability for HIV/AIDS patients to be infected by Hepatitis B virus when have these risk factors is equal to 88.18%. Other variables that did not affect the influence of occurrence of Hepatitis B virus in HIV/AIDS patients were ,Age, gender, marital status, and level of education.
Conclusion: The factors that was proven to affect the influence of occurrence hepatitis B virus in HIV/AIDS patients were, CD4≤100 and being male who do sex with other male (MSM).
Key Words: Hepatitis B virus, risk factors, HIV/AIDS patients, RSUP Dr.Kariadi-Semarang

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