YUDHASYAH, RIA ASTARI and BUDISULISTYO, TRIANGGORO and KUSTIOWATI, ENDANG and HUSNI, AMIN and Muhartomo, Hexanto and Suryadi, Suryadi (2023) PERBANDINGAN ANTARA PEMBERIAN INJEKSI TRIAMCINOLON EPIDURAL DENGAN INJEKSI DEKSAMETASON EPIDURAL TERHADAP PERUBAHAN INTENSITAS NYERI DAN GAMBARAN ELEKTROFISIOLOGI PENDERITA HNP SERVIKAL KRONIS. Masters thesis, UNIVERSITAS DIPONEGORO.

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Abstract

Background: Cervical disc herniation (CDH) is the most common cause of radicular pain, which one-third of the population suffered at more than 6 months. Epidural steroid injection is quite commonly performed in this disorder, whether in acute or chronic phases. There are two steroid drugs commonly used: triamcinolone and dexamethasone, which both observed efficacies. This study is aimed at comparing both to neuropathic pain improvement.
Methods: The randomized blinded control trial study was conducted in Dr. Kariadi Semarang in Indonesia. Chronic CDH patients were divided into two groups: Triamcinolone and Dexamethasone, who performed interlaminar cervical epidural injections under fluoroscopic guidance. Our study might run from January 2022 to July 2023, so the PainDETECT scoring was carried out before and 3 Months afterward. Comparison to determine effective therapy using the Mann-Whitney test, and significantly defined p
<0.05.
Results: Forty-two subjects were involved in the study, Dexamethasone 21 and Triamcinolone 21 people. After dexamethasone injection 4 of the 5 remained nociceptive, 7 of the 7 unclear pain became nociceptive, and 5 of the 9 neuropathic pain became unclear pain. The results of the marginal homelessness test obtained a p-value <0.001, which means that there was a significant difference in pain scores before and after epidural dexamethasone injection. The results of the marginal homelessness test obtained a value of p
= 0.007, which means that epidural triamcinolone injection has an effect on pain scores in chronic CDH patients.
Conclusion: Dexamethasone might be use for treating chronic neck pain due to CDH being more effective than Triamcinolone.

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