NINGSIH, Sri Wahyuni and Suhartono, Suhartono and Laksono, Budi (2023) ANALISIS LUARAN MATERNAL DAN PERINATAL PADA IBU HAMIL TERINFEKSI COVID-19 Studi Kasus di RSUP Dr. Kariadi Kota Semarang Periode Tahun 2021. Masters thesis, UNIVERSITAS DIPONEGORO.

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Abstract

Latar belakang. Ibu hamil merupakan kelompok yang paling rentan terinfeksi COVID-19. Wanita yang sedang hamil mengalami perubahan pada tubuh dan imunitasnya sehingga dapat berisiko terhadap infeksi COVID-19. Kehamilan dengan infeksi COVID-19 dapat menyebabkan morbiditas dan mortalitas maternal serta perinatal. Namun belum dilakukan analisis lebih lanjut mengenai hubungan infeksi COVID-19 dengan luaran maternal dan perinatal pada ibu hamil.
Tujuan. Menganalisis luaran maternal dan perinatal pada ibu hamil terinfeksi COVID-19 dan tanpa COVID-19 di RSUP Dr. Kariadi Kota Semarang. Metode. Penelitian ini menggunakan studi kohort retrospektif dan pengambilan sampelnya menggunakan metode consequtive sampling. Populasi kasus dalam penelitian ini adalah Ibu hamil yang terinfeksi COVID-19 sedangkan populasi kontrolnya adalah ibu hamil tidak terinfeksi COVID-19 yang memiliki rekam medik pada periode Januari-Desember 2021. Sampel terdiri dari 100 ibu hamil terinfeksi COVID-19 dan 100 ibu hamil tanpa COVID-19. Analisis data menggunakan Uji Chi Square, kemudian dilanjutkan dengan Multivariate Regresi Logistik.
Hasil. Dari hasil analisis statistik, didapatkan bahwa infeksi COVID-19 memiliki hubungan signifikan dengan kejadian luaran maternal adalah Sectio Caesaria (p=0,001; RR=2,00, 95% CI 1,411 – 2,836), ARDS (p=0,005; RR=6,50, 95% CI 1,506-28,064) admisi ICU (p=0,005; RR=6,50, 95% CI 1,506-28,064) dan Mortalitas Maternal (p=0,003; RR=12,00, 95% CI 1,590–90,557). Sedangkan luaran perinatal tidak ada yang berhubungan dengan infeksi COVID-19.
Kesimpulan. COVID-19 berisiko terhadap luaran maternal dan perinatal pada ibu hamil sehingga dibutuhkan pemeriksaan kesehatan ibu hamil secara rutin dan peningkatkan protokol kesehatan untuk mencegah terjadinya penularan.
Kata kunci: COVID-19, Ibu Hamil, Luaran Maternal, Luaran Perinatal

Background. Pregnant women are the group most vulnerable to being infected with COVID-19. Women who are pregnant experience changes in their body and immunity so they may be at risk of COVID-19 infection. Pregnancy with COVID-19 infection can cause maternal and perinatal morbidity and mortality. However, further analysis has not been carried out regarding the relationship between COVID-19 infection and maternal and perinatal outcomes in pregnant women.
Objective. Analyzing maternal and perinatal outcomes in pregnant women infected with COVID-19 and without COVID-19 at RSUP Dr. Kariadi Semarang City. Method. This research uses a retrospective cohort study and the sample collection uses the consecutive sampling method. The case population in this study is pregnant women infected with COVID-19, while the control population is pregnant women not infected with COVID-19 who have medical records for the period January-December 2021. The sample consists of 100 pregnant women infected with COVID-19 and 100 pregnant women without COVID-19. Data analysis used the Chi Square Test, then continued with Multivariate Logistic Regression.
Results. From the results of statistical analysis, it was found that COVID-19 infection had a significant relationship with the incidence of maternal outcomes, namely Sectio Caesaria (p=0.001; RR=2.00, 95% CI 1.411 – 2.836), ARDS (p=0.005; RR=6, 50, 95% CI 1.506-28.064) ICU admission (p=0.005; RR=6.50, 95% CI 1.506-28.064) and Maternal Mortality (p=0.003; RR=12.00, 95% CI 1.590–90.557) . Meanwhile, there were no perinatal outcomes related to COVID-19 infection.
Conclusion. COVID-19 poses a risk to maternal and perinatal outcomes in pregnant women, so routine health checks for pregnant women and increased health protocols are needed to prevent transmission.
Keywords: COVID-19, Pregnant Women, Maternal Outcome, Perinatal Outcome

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