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HUBUNGAN JENIS PENYAKIT JANTUNG BAWAAN TERHADAP KADAR HORMON TIROID

Soegiarto, Monica Katherina and soetadji, anindita and Utari, Agustini (2022) HUBUNGAN JENIS PENYAKIT JANTUNG BAWAAN TERHADAP KADAR HORMON TIROID. Masters thesis, universitas diponegoro.

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Abstract

Latar belakang: Penyakit jantung bawaan merupakan penyakit jantung struktural atau fungsional yang ada sejak lahir dan malformasi jantung. Angka kejadian PJB mencapai 25% dari semua anomali kongenital serta menjadi masalah kesehatan global. Efek hormon tiroid pada miosit jantung berhubungan erat dengan fungsi jantung terutama pada anak dengan PJB. Akan tetapi publikasi penelitian mengenai pengaruh jenis- jenis PJB terhadap kadar hormon tiroid masih sangat terbatas.

Tujuan: Mengetahui hubungan jenis penyakit jantung bawaan terhadap kadar hormon tiroid dan faktor- faktor yang mempengaruhinya.

Metode: Penelitian cross sectional di poliklinik kardiologi RSUP Dr. Kariadi Semarang terhadap 48 anak PJB yang belum dikoreksi usia 6 bulan -5 tahun dilakukan pemeriksaan kadar hormon tiroid FT4 dan TSHs.

Hasil: Didapatkan rerata kadar TSHs 4,13 ± 2,51mlU/l pada PJB asianotik dan 2,50 ± 1,38 mlU/l pada PJB sianotik. Sedangkan nilai FT4 0,90 ± 0,27 ng/dl pada PJB asianotik dan 0,77 ± 0,30 ng/dl pada PJB sianotik. Hubungan jenis PJB dengan kadar hormon tiroid, jenis PJB dengan status gizi dan kadar hormon tiroid dengan status gizi didapatkan nilai p< 0.05.

Kesimpulan: Tidak terdapat hubungan jenis PJB terhadap kadar hormon tiroid, tidak terdapat hubungan jenis PJB dengan status gizi dan tidak terdapat hubungan kadar hormon tiroid dengan status gizi.

Kata Kunci: PJB, hormon tiroid, TSHs, FT4, status nutrisi

Item Type: Thesis (Masters)
Uncontrolled Keywords: PJB, hormon tiroid, TSHs, FT4, status nutrisi
Subjects: Medicine
Divisions: Faculty of Medicine > Master Program of Specialist Medical
Depositing User: Upload Mandiri FK
Date Deposited: 30 Dec 2022 03:49
Last Modified: 05 Sep 2024 03:24
URI: https://eprints2.undip.ac.id/id/eprint/10754

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